Two operations repair an abdominal aneurysm. Endovascular aneurysm repair, EVAR, lines the aneurysm from inside with a fabric and metal stent graft passed up from the groin arteries. Open repair replaces the weak segment with a fabric tube through an incision in the abdomen.
Long-term results
Three large randomized trials, in Britain, the Netherlands and the United States, compared the two repairs in patients fit for either, and their follow-up has now reached twelve to fifteen years, long enough to see how the stent grafts hold up as patients age. The answers differ in detail.
The British EVAR trial 1
Patel and colleagues randomized 1,252 patients with aneurysms of at least 5.5 cm. In the first six months, deaths ran lower after EVAR. Beyond eight years, open repair came out ahead, mainly because sacs ruptured later after EVAR, 13 deaths against two, in patients whose grafts had developed leaks.
EVAR has an early survival benefit but an inferior late survival compared with open repair, which needs to be addressed by lifelong surveillance of EVAR and re-intervention if necessary.
EVAR trial 1, 1,252 patients, Lancet, 2016
The trials agree on four points.
- EVAR carries a lower risk around the operation itself.
- Long-term survival ends up close after both.
- EVAR needs more secondary procedures to seal leaks.
- After EVAR, scans must continue for life.
Recovery and the stay in Istanbul
How long you stay
Plan seven to ten days in Istanbul after EVAR, including the first check scan, and two to three weeks after open repair. Coordinators speaking English, Arabic, French, Russian, Serbian, Romanian or Spanish arrange the airport, the hotel and interpreters, and a companion can sleep in your room.
1
EVAR
Walking the same evening or next morning, home from hospital on day two or three, a check CT before you fly.
2
Open repair
A night in intensive care, eating within days, walking daily, home from hospital at seven to ten days, full recovery over two to three months.
Life after repair
Daily life
Driving after a week following EVAR and after four to six weeks after open repair. No heavy lifting for six weeks after open surgery, while the abdominal wall heals and before the scar has the strength to hold against straining. Keep taking blood pressure and cholesterol medicines. Stay off cigarettes.
Follow-up after you return home runs through your coordinator. The schedule follows.
- A CT scan at one month after EVAR, sent to our team.
- A scan at twelve months.
- Then ultrasound or CT every year for life after EVAR, and every five years after open repair.
Planning the trip
Cost and paperwork
The cost depends on the repair, the stent graft, the nights in hospital and any added procedure on the iliac arteries. The estimate after the free review lists each part, and the coordinator prepares the visa letter.
Flying after repair
Short flights after a week following EVAR, long-haul flights after the check scan, and two to four weeks after open repair, with compression stockings and a walk every hour.
Bringing your records
Bring every CT on disc, the reports, a list of medicines and any heart test results. Your original scans let us measure growth precisely.
The American OVER trial
Fourteen years of follow-up
Lederle and colleagues followed 881 veterans for up to 14 years. Deaths ran at 68.0 percent after EVAR and 70.0 percent after open repair, with no significant difference at any point, aneurysm-related deaths at 2.7 and 3.7 percent, and more secondary procedures after EVAR. Unlike the British trial, late survival did not favor open repair.
Aortic aneurysm repair FAQ
At what size should an aortic aneurysm be repaired?
At 5.5 cm in men and 5.0 cm in women, or sooner if it grows more than 1 cm in a year or causes pain.
Is EVAR better than open surgery?
EVAR is safer around the operation and gets you home sooner. Over ten to fifteen years survival ends up close, and EVAR needs lifelong scans and more repeat procedures.
Can a small aneurysm be left alone?
Yes, with regular ultrasound scans. Repairing small aneurysms early gave no survival benefit in trials.
How long will I stay in Istanbul?
Seven to ten days after EVAR and two to three weeks after open repair.
Can my son or daughter stay with me?
Yes. One relative sleeps in your room throughout, and the coordinator books the hotel for the days after discharge.
References
- UK Small Aneurysm Trial Participants. Mortality results for randomised controlled trial of early elective surgery or ultrasonographic surveillance for small abdominal aortic aneurysms. Lancet. 1998;352(9141):1649-1655.
- Brown LC, Powell JT. Risk factors for aneurysm rupture in patients kept under ultrasound surveillance. Annals of Surgery. 1999;230(3):289-296.
- Ashton HA, Buxton MJ, Day NE, et al. The Multicentre Aneurysm Screening Study (MASS) into the effect of abdominal aortic aneurysm screening on mortality in men: a randomised controlled trial. Lancet. 2002;360(9345):1531-1539.
- Patel R, Sweeting MJ, Powell JT, Greenhalgh RM. Endovascular versus open repair of abdominal aortic aneurysm in 15-years' follow-up of the UK endovascular aneurysm repair trial 1 (EVAR trial 1): a randomised controlled trial. Lancet. 2016;388(10058):2366-2374.
- Lederle FA, Kyriakides TC, Stroupe KT, et al. Open versus endovascular repair of abdominal aortic aneurysm. New England Journal of Medicine. 2019;380(22):2126-2135.