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Laparoscopic Prostatectomy
Urology

Laparoscopic Prostatectomy

About This Department

 
LAPAROSCOPIC PROSTATECTOMY

Small wounds are what gets advertised. Gas, tilt and rigid instruments are what it is.

Keyhole removal of the prostate inflates your abdomen with carbon dioxide, tips you head down for several hours and works through straight instruments that cannot bend at the tip. Each of those three shapes your week, your anesthetic assessment and your surgeon's difficulty. This page covers all three, and it reports honestly where the randomized evidence favors a robot instead.

No difference
In continence at 12 months between keyhole and robotic surgery, pooled from randomized trials in 1,205 men
4 times
The odds of potency at 12 months with a robot, in men potent beforehand who had nerve sparing
10 mmHg
Rise in eye pressure by the end of the head down tilt, back to baseline once the table is levelled
Free
Written opinion on whether the keyhole route suits your anatomy and your health before you travel
Free consultation

The keyhole version, described plainly

Five or six small cuts take the instruments in, ranging from five to twelve millimeters, and carbon dioxide inflates the space so the surgeon has somewhere to work. A camera on a rod supplies the picture. The instruments are straight metal rods with jaws at the end, passed through valved tubes in the abdominal wall, and each one pivots at the point where it enters you, so the handle moves one way and the tip moves the other. Surgeons learn to reverse that instinct and never quite stop noticing it. The operation performed inside is the same one described on our radical prostatectomy page, with the same gland removed and the same join made between bladder and urethra afterward. What differs is the route in, the view, the physiology of lying inflated and tipped for several hours, and the difficulty of sewing that join through rods that cannot bend at the tip.

The surgeon stands at the table throughout, holding those rods, watching a screen above your knees.

What actually defines this approach

The missing wrist
A straight laparoscopic instrument can go in and out, swing in two directions around the port, roll along its own axis and open its jaws. A robotic instrument adds a hinged wrist behind the jaws, which gives two more directions of movement inside the body. That difference sounds small and it decides how hard one particular task becomes, namely sewing a circular join between bladder and urethra deep in the pelvis with the needle approaching at whatever angle the port allows. Everything else in the operation transfers between the two. Suturing at depth is where the wrist earns its money, and a surgeon who has spent years sewing that join with rigid rods has acquired a skill most of his younger colleagues will never need.

How to use this page

Sections one to six describe what the approach does to your body and which patients it suits poorly. Sections seven to nine cover the evidence comparing it with a robot and how to read the numbers a clinic quotes you. The rest is practical.

Three features, three consequences

Each of the three has a downstream effect that shows up somewhere in your care, and none of them appears in the brochure photograph of four small dressings.

1
Carbon dioxide under pressure inside your abdomen, which pushes the diaphragm up, gets absorbed into your blood and has to be breathed out for you by a ventilator.
2
A head down tilt of around 25 to 30 degrees for the whole operation, which slides your organs away from the pelvis and raises the pressure in your head, your eyes and your chest.
3
Rigid instruments with no wrist, which makes the reconstruction at the end the hardest thing any urologist does and makes surgeon experience count for more here than anywhere else.

This table scrolls sideways on a narrow screen. Drag or swipe to see every column.

The three routes, compared on the features that genuinely differ
Feature Open Keyhole Robotic
Gas in the abdomen None Yes, for the whole operation Yes, for the whole operation
Head down tilt Slight Steep, sustained Steep, sustained
Wrist at the instrument tip The surgeon's own None Mechanical, inside the body
Where the surgeon stands At the table, hands inside you At the table, holding rods At a console across the room
Wounds you go home with One incision, hand span or shorter Five or six, five to twelve millimeters Five or six, five to twelve millimeters

Through the abdomen or behind it

Two routes reach the prostate through small ports and this choice exists only in keyhole surgery. The transperitoneal route enters the abdominal cavity proper, moves bowel aside and comes down onto the bladder from above, giving a wide working space and a familiar layout, while the extraperitoneal route inflates the layer of fat and connective tissue in front of the bladder without ever opening the cavity, so the bowel stays where it is and the space stays small, dark and immediate. Surgeons have preferences that are close to religious on this point, and the published comparisons are calmer than the surgeons are. Two practical differences hold up. Staying outside the abdominal cavity keeps bowel out of the field and confines any leak from the join to a small pocket away from the intestines, and opening the cavity gives room for a long node dissection and a view that most trainees learned the anatomy on.

What the pooled comparisons found

Thirteen studies covering 1,674 men who had keyhole prostatectomy were pooled, split almost evenly between the two routes at 850 and 824, and operating time came out the same across them, as did blood loss, transfusion rate, complications during the operation and the chance of converting to open surgery. One difference reached significance. Complications after the operation were more frequent in the transperitoneal group, with an odds ratio of 1.69 and a confidence interval running from 1.23 to 2.32.

And the same question in robotic series

Sixteen studies covering 3,897 robotic operations asked it again and found the same direction with sharper numbers. Going behind the peritoneum instead of through it saved around fourteen minutes of operating time, sent men home most of a day sooner, and cut two specific problems by roughly four fifths, namely a sluggish bowel afterward and a groin hernia appearing later. Total complications, blood loss, margin status and continence at six months all matched. Neither route is better at removing the prostate. One of them disturbs less on the way past. The hernia figure deserves its own line, since a groin hernia showing up a year after prostate surgery gets put down to bad luck by the man it happens to and traced back to the operative route by anybody reading the pooled numbers, and a difference of that size in something requiring a second operation to repair belongs inside a consent conversation.

When the choice gets made for you
Previous surgery inside the abdomen leaves adhesions that make the transperitoneal route slow and hazardous, so extraperitoneal wins by default there. Previous hernia repair with mesh in the groin can obliterate the extraperitoneal space and push the decision the other way. A very large prostate, or a plan that includes an extended lymph node dissection reaching up to the common iliac vessels, favors the roomier transperitoneal approach. Anybody who cannot tolerate a steep tilt does better extraperitoneally, since the bowel never needs moving and the tilt can be less extreme. Tell us about every previous operation on your abdomen or groin, including the ones you consider too old to matter.

The gas

Carbon dioxide gets chosen because it dissolves readily in blood and will not burn, and it runs at a pressure somewhere between twelve and fifteen millimeters of mercury in most units. That pressure does three things at once. It lifts the abdominal wall away from the organs and creates the working space, it presses on the veins returning blood to the heart, and it pushes the diaphragm upward so the lungs have less room to expand, and all the while the gas is being absorbed steadily through the lining of your abdomen into the bloodstream, where it turns into acid that the ventilator has to blow off by breathing you harder than normal. None of this is dangerous in a healthy man and all of it matters in a man whose lungs or heart are already working at their limit.

1
Shoulder tip pain, sharp and one sided, from gas left under the diaphragm irritating a nerve that reports to the shoulder. It peaks on day one and clears in two or three days.
2
Bloating and a tight abdomen for several days, which walking shifts faster than lying still does.
3
Occasionally a crackling feeling under the skin of the abdomen, chest or neck where gas has tracked into the tissues. It looks alarming, it resolves without treatment, and it gets checked rather than ignored.

Ask what pressure the unit works at. Fifteen is common, twelve is kinder to the circulation, and units that have thought about it will have an opinion ready.

The tilt

Reaching the prostate with instruments that come from above requires the bowel to fall away from the pelvis, gravity does that job when the table tips your head down by twenty five or thirty degrees, and you stay there for the whole operation, strapped and padded so that you do not slide. Blood pools in your head and chest. Pressure rises inside your skull and inside your eyes, your face and eyelids swell, and your lungs get squeezed from below by the gas and from above by nothing at all. Every one of those effects reverses when the table is levelled, which is the single most reassuring fact in this section and the reason the position is used so widely.

Somebody measured the eye part properly. In 59 men without glaucoma, eye pressure was recorded at six points through the operation. Anesthesia alone dropped it by 6.5 millimeters of mercury, an hour of gas and tilt raised it by 7.3, and by the end of the tilt it had climbed 10.2 above the starting value. Levelling the table brought it back, with the reading after return to flat sitting at 20.1 against 20.0 before anything began, and men whose operation ran beyond four hours finished with higher pressures than men whose operation ran under four. No eye complications occurred in any of them.

Length of the operation is therefore an eye variable as well as a surgical one.

A separate randomized trial of 66 men found that the anesthetic drug changes the size of the rise. Thirty minutes into the tilt, men maintained on a gas anesthetic had eye pressures averaging 23.5 while men maintained on intravenous propofol averaged 19.9, and the climb from baseline was 6.0 against 2.1. Nobody in either group came to harm, so this is no reason for alarm, and it is a reason for any man with glaucoma or raised eye pressure to make sure the anesthetist knows well before the day, since a drug choice that costs nothing removes most of the rise.

Who the keyhole route suits poorly

Almost nobody gets refused outright, and several conditions change the plan enough that they have to be declared before a date is booked. Glaucoma and any history of raised eye pressure belong at the top of that list, along with previous retinal surgery, and severe emphysema or chronic bronchitis belongs just under them, because the ventilator has to clear absorbed carbon dioxide on top of your normal load and a pair of lungs already working at capacity has nothing left to give. Heart failure that is poorly controlled reacts badly to both the pressure on the returning veins and the volume shift from the tilt. Raised pressure inside the skull, a shunt, or recent brain surgery rules the steep position out until a neurosurgeon says otherwise. Carrying a lot of weight belongs here too, in a quieter way. A heavy abdomen presses harder on the diaphragm once the gas goes in and the table tips, so the ventilator runs at higher pressures and the anesthetist watches more closely, and a man with untreated sleep apnea on top of that deserves a proper assessment before any date gets offered, since a reassuring email is no substitute for one.

Three more belong on the list for surgical rather than medical reasons.

Extensive previous abdominal surgery makes the transperitoneal route slow and pushes us behind the peritoneum, and prior pelvic radiotherapy scars every plane the operation depends on and turns a keyhole case into a genuinely difficult one, so a man who has had it belongs with the most experienced surgeon in the building. A very large prostate reduces the space in an already small pelvis, and while size alone stops nothing, it lengthens the operation, which by the previous section is also an eye and lung variable. Send us your height and weight, your medication list and your eye history with the rest of your documents, since these are the things that change our answer rather than your PSA.

Converting to open surgery

Occasionally a keyhole operation becomes an open one partway through. Bleeding that will not settle under gas pressure, adhesions that refuse to release, a view that has gone, an injury that needs repairing directly, or equipment that fails. Rates in published keyhole series are low and the pooled comparison of the two access routes found no difference between them, with the confidence interval on that comparison running so wide that the plain statement is simply that conversions are too uncommon to compare reliably. Conversion itself is undramatic from the inside. The ports come out, a lower abdominal incision goes in, the same operation carries on under direct vision, and the surgeon finishes with his hands where his instruments had been.

Treat conversion as a decision and not as an accident. A surgeon who converts when the view is poor has chosen your safety over his statistics, and a surgeon who has never converted in his career is either extraordinary or selecting his patients very carefully.

Consent forms should mention it. Ours does.

Keyhole against robotic

Robotic surgery has replaced conventional keyhole surgery across most of the wealthy world, at substantially higher cost, and the justification offered was better functional results from finer dissection of the nerve bundles. Two things made that claim hard to test properly. Randomizing a man between a machine he has read about for years and a technique he has never heard of takes a consent conversation most units would sooner avoid, and a surgeon equally skilled at both approaches is rare enough that trials kept running short of them. Five teams managed it anyway across two decades, and somebody finally pooled what they produced. Five randomized trials were identified, three teams supplied individual patient data, one contributed published figures, and the fifth had closed early for poor recruitment, leaving 1,205 randomized men in the analysis.

  • Continence at twelve months showed no significant difference between the two approaches, with an odds ratio of 1.95 and a confidence interval running from 0.67 all the way to 5.62, a span that comfortably includes no effect at all.
  • At three months and at six months the robot was ahead, significantly, so men who had robotic surgery got dry sooner and ended up in the same place.
  • Potency told a different story. Among men who were potent beforehand and had a nerve sparing operation, the odds of being potent at twelve months were four times higher after robotic surgery, with a confidence interval from 1.63 to 10.09.
  • Cancer control measures, margins and further treatment showed nothing separating the two approaches.
What we tell men who ask us directly
A man whose erections work well, who wants them back, and who is a candidate for sparing both nerve bundles has a real argument in favor of a robot, and that argument comes from randomized data rather than from a brochure. A man whose erections have already gone, or whose cancer makes nerve sparing impossible on both sides, is being offered a benefit he cannot collect. Continence ends up level either way, with the robot getting there faster. Weigh that finding against the experience of the specific surgeon in front of you, because a busy keyhole surgeon and an occasional robotic one are not the comparison the trials made. We would rather say this plainly than have you read it somewhere else afterward.

How to read a continence figure

Every clinic quotes a continence percentage and almost none of them state which definition produced it. Three definitions are in common use, namely no pads at all, no pads or one thin safety pad worn for reassurance, and no more than one pad of any kind, and those three applied to the very same group of men produce numbers that differ by more than any surgical technique ever has. Picture a hundred men a year after surgery. Sixty of them use nothing. Twenty keep a thin pad in a pocket for reassurance and rarely use it, and twenty wear one every day. The strict definition calls that sixty percent continent. The safety pad definition calls it eighty. The loosest definition calls it a hundred.


Investigators on a randomized multicenter trial took 718 men and tested each definition against the one thing that ought to settle it, which is whether the man himself answers yes when asked if he suffers from incontinence. At three months the safety pad definition matched his own view best, at six months and at twelve the strict no pad definition matched best, and the loosest definition agreed poorly at every single time point. The authors recommended that everybody report the zero pad figure and stop mixing definitions.

The practical use of that finding
When a clinic sends you a continence figure, reply with one sentence asking which definition it uses and at what time point. A unit quoting 95 percent on the loosest definition at twelve months and a unit quoting 80 percent on the strict definition at twelve months may well be describing identical results, and only one of them has told you anything. The number to compare across units is the share of men using no pad at all at twelve months. Anything else is a different question wearing the same percentage sign.

The day and the week after

Fasting from midnight, a morning list where possible, and a general anesthetic with a breathing tube. Two to four hours inside. You wake with four or five dressings the size of a coin, a catheter, occasionally a drain, and a sore throat from the tube. Nurses will have you upright the same evening, which shifts trapped gas and lowers the clot risk at the same time. Most men eat a light meal the next day and leave on the second or third. Before any of that, the surgeon marks where the ports will go, following the shape of your abdomen and any scar already sitting on it, and a dose of antibiotic runs in as the anesthetic starts. A drain stays for a day where the join needed extra work or the node dissection was extended, coming out once the fluid through it turns clear and small in volume. The sore throat from the breathing tube fades inside a day and takes more men by surprise than the wounds do.

The wounds and the bloating

Port wounds need very little. Keep them dry for two days, then shower normally and pat them dry, and expect a little bruising that spreads downward under gravity and looks worse on day four than on day two. The twelve millimeter sites carry a stitch in the deeper layer, which is what stops a hernia forming there later on, and those two ache longest and feel tight for a week or so afterward. Bloating and the pressure of gas take three or four days to settle, and walking clears it faster than any medicine. Shoulder tip pain surprises men who were warned about their abdomen and nothing else.

The catheter and the return to ordinary life

The catheter stays seven to fourteen days regardless of the approach, since the join inside heals on its own timetable and takes no notice of how the surgeon reached it, and lifting stays off the list for six weeks so that the deep stitches at the port sites hold while they do their work. Desk work resumes at two weeks and physical work at six. Driving waits until an emergency stop produces no hesitation, which for most men falls in the third week. Leakage after the catheter comes out follows exactly the pattern described on our radical prostatectomy page, since the reconstruction is identical.

Choosing a unit for this operation

Conventional keyhole prostatectomy rewards experience more steeply than the other two approaches, so the questions below aim at the surgeon rather than the hospital. Send them by message and read the replies against each other. Four questions cost you one message each and they sort units faster than any amount of website reading. Use identical wording for every unit you write to, since a question phrased a little differently comes back answered a little differently and the comparison then means nothing.

  • How many laparoscopic radical prostatectomies has the named surgeon performed in his career, and how many in the last twelve months.
  • Which route does he use for this operation, through the abdomen or behind it, and what specifically would make him change that plan in my case.
  • What share of his own patients uses no pad at all at twelve months, counted by questionnaire and not by memory.
  • How often does he convert to open surgery, and what were the reasons the last few times.

Wide table. Scroll sideways on a narrow screen to reach the last column.

Reading the replies you get
Question A serious reply A reply to be wary of
Case numbers Two figures for one named surgeon on this approach A hospital total covering every urological operation
Route A preference with the reasons it would change Whichever one the question implied you wanted
Continence A percentage with its definition and its time point A percentage on its own, or a word instead of a number
Conversion A low rate and a willingness to describe the cases Never happens here

Cost, travel and flying home

Set aside eleven to fifteen nights. Two go on arrival, bloods, anesthetic review and an eye pressure check where your history calls for one, two or three on the hospital, and the remainder on the stretch between discharge and catheter removal, ending with a review the day before you leave.

Clearance to board comes when you walk without difficulty, run no fever, have no wound discharge and are passing urine after the catheter comes out, which most men reach between day eight and day twelve, and gas trapped in the abdomen expands slightly in a cabin, so an early flight while still bloated is uncomfortable and not dangerous, with the extra days of waiting proving easier than explaining a miserable journey afterward. Clot risk stays above normal for several weeks after pelvic surgery, so we supply stockings, prescribe injections where a node dissection was done, and ask you to walk the cabin every hour. Going home with the catheter still in place works cleanly when a doctor at your end has agreed in writing to remove it, and we forward the operation note, the removal instructions and our direct line before you fly.

Four things move what this operation costs. The route and whether a lymph node dissection is included, the number of hospital nights, whether pathology on the whole specimen sits inside the quoted figure, and whether the follow up visits before departure are counted separately. Ask for all four in writing.

Send us the biopsy report with the grade group and the positive core count, the prostate MRI report together with the images on a disc or a link, your PSA history with dates, any bone or PSMA scan, a full medication list, your height and weight, and a note of every previous operation on your abdomen, groin or eyes. A urologist reads all of it and writes back at no charge, including the replies that say the keyhole route suits you poorly or that surgery suits you poorly. One coordinator then stays with you from that first message until you are home, reachable on WhatsApp afterward for as long as you need her. English, Arabic, French, Russian, Serbian, Romanian and Spanish are spoken in the building, anything else gets interpreted on request, your companion sleeps in the room, hotel and airport transfers are booked around the operating date, halal, vegetarian and diabetic meals are ordinary here, a prayer room sits on the ground floor, and the visa invitation letter goes out roughly ten days ahead. Once you are home, send the six week PSA and every result after it and a urologist here will read them without a fee.

No prices appear on this page. Any figure offered before a urologist has read your scan was picked to win an inquiry.

Laparoscopic prostatectomy FAQ

Seven questions reach us every week from men weighing this against a robot.

Is keyhole surgery worse than robotic surgery?
For cancer control and for continence at twelve months, the pooled randomized evidence in 1,205 men found no difference. Robotic surgery got men dry faster at three and six months. For potency at twelve months in men who were potent beforehand and had nerve sparing, robotic surgery was four times more likely to deliver it. Which of those findings applies to you depends entirely on your erections now and on whether both nerve bundles can be spared.
Why does my shoulder hurt after abdominal surgery?
Gas left under the diaphragm irritates a nerve that also serves the shoulder, so your brain places the pain there. It is sharp, usually one sided, worst on the first day and gone within three. Walking, simple painkillers and warmth all help. Shoulder pain that arrives with breathlessness or a fever is a different problem and needs looking at.
I have glaucoma. Can I still have this operation?
Usually yes, with preparation. Eye pressure rises through the head down tilt and returns to baseline once the table is levelled, and a randomized trial showed that maintaining anesthesia with intravenous propofol instead of a gas agent cuts the rise from around 6 to around 2 millimeters of mercury. Tell us before you book so the anesthetist plans for it, and expect us to ask for a recent note from your eye doctor.
Which route is better, through the abdomen or behind it?
Cancer results and continence match. Going behind the peritoneum produced fewer complications afterward in pooled keyhole data and, in robotic series, shorter operations, shorter stays, less bowel sluggishness and fewer groin hernias later. Previous abdominal surgery or previous groin mesh can decide it for you, so the answer belongs to your history rather than to a general rule.
What happens if it has to be converted to open surgery?
The surgeon makes a lower abdominal incision and finishes the same operation directly. You wake with a longer wound, stay a day or two longer and recover a little more slowly, and the cancer operation itself is unaffected. Conversions are uncommon, and the reasons are bleeding, adhesions, a lost view or an injury that needs direct repair.
Will the small wounds mean less leakage afterward?
No. Leakage comes from the sphincter and the reconstruction deep in the pelvis, which are the same whichever route reached them. Small wounds buy you less blood loss, a shorter stay and a faster return to ordinary movement. Anybody selling keyhole surgery on continence grounds is selling something the evidence does not support.
How long will we need to stay in Istanbul?
Eleven to fifteen nights covers workup, surgery, two or three hospital nights, catheter removal and a review. Book a changeable return ticket. Clearance to fly arrives for most men between day eight and day twelve, and traveling with the catheter still in is fine when removal is arranged and confirmed at your end.

References

  1. Haney CM, Kowalewski KF, Westhoff N, Holze S, Checcuci E, Neuberger M, et al. Robot-assisted versus conventional laparoscopic radical prostatectomy, a systematic review and meta-analysis of randomised controlled trials. European Urology Focus. 2023;9(6):930-937.
  2. Holze S, Kuntze AS, Mende M, Neuhaus P, Truss MC, Do HM, et al. Assessment of different continence definitions in the context of the randomized multicenter prospective LAP-01 trial. European Journal of Medical Research. 2024;29(1):58.
  3. Wang K, Zhuang Q, Xu R, Lu H, Song G, Wang J, et al. Transperitoneal versus extraperitoneal approach in laparoscopic radical prostatectomy, a meta-analysis. Medicine. 2018;97(29):e11176.
  4. Uy M, Cassim R, Kim J, Hoogenes J, Shayegan B, Matsumoto ED. Extraperitoneal versus transperitoneal approach for robot-assisted radical prostatectomy, a contemporary systematic review and meta-analysis. Journal of Robotic Surgery. 2022;16(2):257-264.
  5. Shirono Y, Takizawa I, Kasahara T, Maruyama R, Yamana K, Tanikawa T, et al. Intraoperative intraocular pressure changes during robot-assisted radical prostatectomy, associations with perioperative and clinicopathological factors. BMC Urology. 2020;20(1):26.
  6. Yoo YC, Shin S, Choi EK, Kim CY, Choi YD, Bai SJ. Increase in intraocular pressure is less with propofol than with sevoflurane during laparoscopic surgery in the steep Trendelenburg position. Canadian Journal of Anesthesia. 2014;61(4):322-329.

Editor's note

Written by the Biruni Hospital medical editorial team. Reviewed by Assoc. Prof. Dr. Emre SALABAŞ, Urology.

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