None of them restores lost sight.
The nerve fibers that carried it are gone, and the aim from here on is to keep the rest. A patient who has lost part of the field should be treated promptly, before another year of watching takes more of it.
What are the options?
Four, in rising order of strength and effort.
From laser to microscopic stents
Selective laser trabeculoplasty
A laser aimed at the eye's drainage meshwork, through a contact lens, in the clinic. It takes five minutes, needs only numbing drops, and the patient goes home at once. The LiGHT trial randomized 718 newly diagnosed patients in the United Kingdom to laser first or drops first. At three years, 74.2 percent of the laser group needed no drops to keep their pressure at target, eleven patients in the drops group needed glaucoma surgery against none in the laser group, and quality of life was the same.
The effect fades over years in many eyes and the laser is repeatable. It suits open-angle glaucoma and raised pressure without advanced damage, and it is the first step for many patients who would otherwise face drops for life.
Selective laser trabeculoplasty should be offered as a first-line treatment for open angle glaucoma and ocular hypertension, supporting a change in clinical practice.
LiGHT trial, 718 patients, The Lancet, 2019
Minimally invasive glaucoma surgery during cataract surgery
Surgeons place several kinds of tiny device in the drainage channel through the same opening used for cataract surgery, adding a few minutes to the operation. In a randomized trial of 240 eyes with mild to moderate glaucoma, 72 percent of eyes that received a trabecular micro-bypass stent with their cataract surgery kept a pressure of 21 or below without drops at one year, against 50 percent with cataract surgery alone, and the safety profile matched cataract surgery.
These devices lower pressure modestly and reduce the number of drops a patient needs, which for someone struggling with three bottles a day is a real gain, while advanced glaucoma needs a larger fall than they give.
This table scrolls sideways on a narrow screen. Swipe or drag to see every column.
Glaucoma procedures side by side
| Procedure |
How it works |
Pressure lowering |
Recovery |
Suits |
| Laser trabeculoplasty |
Laser opens the drainage meshwork |
Moderate |
Same day, back to normal at once |
Early open-angle glaucoma, patients who want to avoid drops |
| Micro-stent with cataract surgery |
Tiny device bypasses the meshwork |
Modest |
As for cataract surgery |
Mild to moderate glaucoma in an eye that needs cataract surgery |
| Trabeculectomy |
A new drainage channel under the white of the eye, with an antiscarring drug |
Largest |
Several weeks, frequent visits |
Advanced glaucoma, low target pressure |
| Drainage tube |
A tube carries fluid to a plate behind the eye |
Large |
Several weeks |
Eyes with previous surgery or a failed trabeculectomy, and complex glaucomas |
Advanced glaucoma, surgery first?
Late diagnosis raises a hard question, drops first or an operation at once. The TAGS trial randomized 453 patients with newly diagnosed advanced glaucoma to trabeculectomy or to escalating drops. After two years quality of life was the same, adverse events were similar, 39 against 44 percent, and the pressure was lower after surgery, 12.4 against 15.1. For an eye with little field left, those few points of pressure can matter, and surgery first is now a reasonable choice that the specialist discusses with each patient.
Trabeculectomy or a drainage tube
When laser and stents are not enough, the choice narrows to two operations.
This table scrolls sideways on a narrow screen. Swipe or drag to see every column.
Tube versus trabeculectomy after five years
| Outcome |
Tube |
Trabeculectomy with mitomycin C |
| Eye pressure |
14.4 mm Hg |
12.6 mm Hg |
| Glaucoma drops needed |
1.4 on average |
1.2 on average |
| Failure over five years |
29.8 percent |
46.9 percent |
| Further glaucoma surgery |
9 percent |
29 percent |
- Previous eye surgery. Eyes that have had cataract surgery or a failed trabeculectomy, the patients in the TVT study, did better with a tube.
- The target pressure. Trabeculectomy reaches lower pressures when it works, useful in advanced disease.
- The type of glaucoma. Glaucoma from new blood vessels, inflammation or scarring usually calls for a tube.
- How often you can be seen. Both need close follow-up, trabeculectomy most of all in the first weeks.
Tube shunt surgery had a higher success rate compared to trabeculectomy with MMC during 5 years of follow-up in the TVT Study.
Tube Versus Trabeculectomy Study, American Journal of Ophthalmology, 2012
Risks of trabeculectomy and tubes
Trabeculectomy can drain too much in the first weeks, leaving a soft eye with blurred vision, or too little if the channel scars. The raised bleb under the upper lid can leak, and it carries a small lifelong risk of infection that can threaten the eye, so a red, sticky eye at any time afterward is an emergency. Cataract develops faster after the operation.
Tubes can also drain too much early on, and later the tube or plate can wear through the covering tissue or shift, needing a repair. Some patients notice double vision from the plate near the eye muscles. Both operations aim at a lower pressure, and both carry the risk of needing another operation, 9 percent after tubes and 29 percent after trabeculectomy over five years in the TVT study.
- A red, painful or sticky eye, at any time, even years later.
- Sudden drop in vision.
- Severe ache with nausea, which can mean the pressure has risen sharply.
- A watery discharge from the eye that does not stop, which can mean a leaking bleb.
The weeks after surgery
After trabeculectomy the surgeon adjusts the flow through the new channel during the first weeks, loosening or cutting stitches with a laser, and may inject antiscarring medicine around the bleb. Visits come every few days at first. Drops for inflammation and infection continue for several weeks, while glaucoma drops in the operated eye stop for the majority.
Tubes follow a similar course. Checks come frequently while the tube starts to drain. Avoid heavy lifting, bending and rubbing for several weeks, and wear a shield at night, because a bleb or a freshly placed tube is at its most vulnerable while the tissues around it are still healing and a single hard rub can undo what the first weeks of careful adjustment have built.
Why trabeculectomy needs you nearby
The first two to three weeks decide whether a trabeculectomy works. The pressure can swing high or low within days, and the fixes, a stitch released by laser or an injection, have to happen at the right moment. A patient who flies home after two days misses that window. We therefore plan two to three weeks in Istanbul for trabeculectomy or a tube, or a hand-over to a glaucoma specialist at home who has agreed in advance to see you within days.
Days, cost and the trip
- Your last three visual field tests and OCT scans of the optic nerve, with dates, so the rate of change can be judged.
- Your pressure readings over time, and every drop you have used, with side effects.
- Any laser or surgery already done on either eye, with the dates and the operation notes if you have them.
- Your general health, medicines and allergies, blood thinners above all.
Days in Istanbul
Laser needs two to three days. That covers the assessment, the laser and pressure checks an hour and a day afterward. A micro-stent with cataract surgery follows the cataract schedule, four to five days for both eyes. Trabeculectomy and tubes need two to three weeks. Fly after the early checks. No gas is placed in the eye. The pressure decides the date of return.
What decides the cost
The procedure decides most of it. Laser costs least, a micro-stent adds the device to the cataract fee, and trabeculectomy and tubes include the operation, the antiscarring drug or the implant, and several weeks of follow-up visits, which are the part quotes leave out most. Packages published by Istanbul hospitals quote trabeculectomy and drainage valves separately, and some describe a two-day stay for trabeculectomy that leaves no time for the checks that decide the result. Ask how many follow-up visits the price includes. Your own figure follows the free review of your tests.
Language, companions and follow-up at home
One coordinator stays with you from the first message. The team works in English, Arabic, French, Russian, Serbian, Romanian and Spanish, and other languages are interpreted on request. An invitation letter naming the hospital and the surgeon goes out ten days before travel, and the international patients office arranges the airport transfer and a hotel or apartment near the hospital for you and a companion, which for a stay of several weeks matters. Halal, vegetarian and diabetic meals are available, there is a prayer room, and a request for a female doctor is passed to the department and met wherever the rota allows. Back home, the coordinator stays reachable on the same WhatsApp number, and the report goes to your own ophthalmologist, since glaucoma needs lifelong monitoring whatever operation is done.
Glaucoma surgery FAQ
Will glaucoma surgery restore my vision?
No. It protects the vision that remains by lowering the eye pressure. Lost vision does not come back, which is why treatment should not be delayed.
Can laser replace eye drops?
For many patients, yes. In the LiGHT trial, 74 percent of patients treated with laser first needed no drops at three years.
Which is better, trabeculectomy or a tube?
In eyes that had previous surgery, tubes failed less often over five years, 29.8 against 46.9 percent. Trabeculectomy can reach lower pressures when it works, and the right choice depends on the eye, its history and how low the pressure needs to go.
How long do I need to stay in Istanbul?
Two to three days for laser, four to five for a stent with cataract surgery, and two to three weeks for trabeculectomy or a tube.
Is glaucoma surgery painful?
It is done under local anesthesia, and most patients feel pressure rather than pain. Discomfort afterward is usually mild and controlled with tablets.
Can my family come with me?
Yes, and for a stay of several weeks a companion helps. The international patients office arranges accommodation near the hospital.
Treatment reduced the intraocular pressure by 25 percent, and progression was less frequent in the treatment group, 45 percent, than in controls, 62 percent.
Early Manifest Glaucoma Trial, Archives of Ophthalmology, 2002
References
- Heijl A, Leske MC, Bengtsson B, et al. Reduction of intraocular pressure and glaucoma progression: results from the Early Manifest Glaucoma Trial. Archives of Ophthalmology. 2002;120(10):1268-1279.
- Gazzard G, Konstantakopoulou E, Garway-Heath D, et al. Selective laser trabeculoplasty versus eye drops for first-line treatment of ocular hypertension and glaucoma (LiGHT): a multicentre randomised controlled trial. Lancet. 2019;393(10180):1505-1516.
- King AJ, Hudson J, Fernie G, et al. Primary trabeculectomy for advanced glaucoma: pragmatic multicentre randomised controlled trial (TAGS). BMJ. 2021;373:n1014.
- Gedde SJ, Schiffman JC, Feuer WJ, et al. Treatment outcomes in the Tube Versus Trabeculectomy (TVT) study after five years of follow-up. American Journal of Ophthalmology. 2012;153(5):789-803.
- Samuelson TW, Katz LJ, Wells JM, Duh YJ, Giamporcaro JE. Randomized evaluation of the trabecular micro-bypass stent with phacoemulsification in patients with glaucoma and cataract. Ophthalmology. 2011;118(3):459-467.